C6749
Cytochrome c equine
recombinant, expressed in E. coli
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About This Item
Recommended Products
biological source
horse
Quality Level
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
powder
UniProt accession no.
storage temp.
−20°C
Gene Information
horse ... CYCS(100053958)
Application
Cytochrome c polymerization occurs by successive domain swapping, which may be a common mechanism of protein polymerization. Cytochrome c has been used in a study to establish that an optimized pulsed-Q dissociation and collision-activated dissociation hybrid workflow may have wide applications in biological and biomedical research.
Biochem/physiol Actions
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell.
Cytochrome c is primarily known as an electron-carrying mitochondrial protein. The transition of cytochrome c between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen
Preparation Note
Produced using animal component-free materials.
Other Notes
View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Journal of molecular biology, 383(2), 437-453 (2008-09-02)
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Protocols
Separation of HPLC protein standard mixture, analytical standard
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