MilliporeSigma
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C1288

Sigma-Aldrich

Complement C6 deficient serum human

for complement assays

NACRES:
NA.61

Quality Level

biological source

human

form

liquid

technique(s)

activity assay: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... C6(729)

Related Categories

Application

Complement C6 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). A deficiency of C6 may result in an increased susceptibility to Neisseria meningitidis. Research has identified that a mutation which leads to a 31 bp deletion in exon 10 in the C6 gene results in C6 deficiency. A coagulation defect has also been observed in mice that are C6 deficient.

Physical form

Supplied as a solution in PBS, pH 7.4

Analysis Note

C6 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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