A8380

5α-Androstan-17β-ol-3-one

≥97.5%

• Synonym(s): 17β-Hydroxy-5α-androstan-3-one, 4,5α-Dihydrotestosterone, Androstanolone, Stanolone
• Empirical Formula (Hill Notation): C₁₉H₃₀O₂
• CAS Number: 521-18-6
• Molecular Weight: 290.44
• Beilstein: 2056371
• EC Number: 208-307-3
• MDL number: MFCD00003667
• PubChem Substance ID: 24891337
• NACRES: NA.77

Properties

• biological source: synthetic
• Quality Level: 200
• sterility: non-sterile
• assay: ≥97.5%
• form: powder
• drug control: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• solubility: ethanol: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
• SMILES string: [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2
• InChI: 1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1
• InChI key: NVKAWKQGWWIWPM-ABEVXSGRSA-N
• Gene Information: human ... AR(367) , ESR1(2099) , PGR(5241) , SERPINA6(866) , SHBG(6462) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Esr1(24890) , Nr3c1(24413) , Nr3c2(25672) , Pgr(25154)

Description

Application

5α-Androstan-17β-ol-3-one, also referred to as androstanolone or dihydrotestosterone, is an anabolic steroid. Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone, including the development of the male phenotype during embryogenesis and at puberty.

Biochem/physiol Actions

Androstanolone is an anabolic steroid. Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty.

Safety Information

• Pictograms: GHS07,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H302 - H351 - H360FD - H410
• Precautionary Statements: P202 - P264 - P270 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Repr. 1A
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves