71729

Sigma-Aldrich

Sodium dodecyl sulfate

≥98.0% (GC)

Synonym(s):
Lauryl sulfate sodium salt, Sodium lauryl sulfate, Dodecyl sulfate sodium salt, SDS, Dodecyl sodium sulfate
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
Beilstein/REAXYS Number:
3599286
EC Number:
MDL number:
eCl@ss:
39093306
PubChem Substance ID:
NACRES:
NA.21

description

anionic

Quality Level

assay

≥98.0% (GC)

mol wt

micellar avg mol wt 18,000

aggregation number

62

loss

≤5% loss on drying

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

H2O: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤200 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

HLB

40

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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Related Categories

Application

Sodium dodecyl sulfate has been used in western blot lysis buffer and also to prepare SDS-loading dye.
Anionic detergent

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all

WGK Germany

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Certificate of Analysis

Certificate of Origin

Resilient Ribonucleases
RNA Methodologies (2010)
Protein expression protocol for an adenylate cyclase anchored by a Vibrio quorum sensing receptor
Beltz Stephanie and Schultz JE
eLife, 259, 168-175 (2016)
Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal
Fazakerley DJ, et al.
eLife, 259, 168-175 (2018)
Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins
Lin P Y, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 259, 168-175 (2017)
Shane Stegeman et al.
Cancer discovery, 5(4), 368-379 (2015-02-19)
Prostate cancer is the second most common malignancy among men worldwide. Genome-wide association studies have identified 100 risk variants for prostate cancer, which can explain approximately 33% of the familial risk of the disease. We hypothesized that a comprehensive analysis...

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