61760
Lectin from Canavalia ensiformis
lyophilized, ≥50% (GE), powder
Synonym(s):
Agglutinin from jack beans, Con A
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About This Item
Recommended Products
biological source
Canavalia ensiformis
Quality Level
form
powder
quality
lyophilized
mol wt
Mr ~53000
concentration
≥50% (GE)
technique(s)
XRF: suitable
storage temp.
2-8°C
Biochem/physiol Actions
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Concanavalin A as a Tool, 639-639 (1976)
Lectins in the isolation of receptors on lymphocytes.
Methods in enzymology, 150, 463-477 (1987-01-01)
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 144, 111576-111576 (2020-08-05)
Plant-derived dietary lectins have been reported to be involved in the pathogenesis of several inflammatory diseases, including hepatitis, inflammatory bowel disease, diabetes, and celiac disease. In this present study, we aimed to assess whether green tea polyphenols (GTPs) exerts protective
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