MilliporeSigma
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46944

Sigma-Aldrich

Fluorescein isothiocyanate–dextran

average mol wt 4,000, (FITC:Glucose = 1:250)

Synonym(s):
FITC-Dextran 4, FITC–Dextran
CAS Number:
MDL number:
NACRES:
NA.32

Quality Level

assay

(FITC:Glucose = 1:250)

mol wt

average mol wt 4,000

concentration

(FITC:Glucose = 1:250)

extent of labeling

~0.004 mol/mol FITC glucose

solubility

H2O: 50 mg/mL, slightly hazy, orange

storage temp.

2-8°C

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Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.
FITC-dextran is used extensively in microcirculation and cell permeability research utilizing microfluorimetry. FITC-dextran has been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran.
FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination
Fluorescein isothiocyanate–dextran (FITC-Dextran 4) is use as a fluorescent probe to study cell permeability. FITC-Dextran 4 is used with to study permeability of epithelial cell such as intestinal and renal cells in vivo.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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