36801

7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester

BioReagent, suitable for fluorescence, ≥96.0% (HPLC)

• Synonym(s): N-Succinimidyl 7-(diethylamino)coumarin-3-carboxylate
• Empirical Formula (Hill Notation): C₁₈H₁₈N₂O₆
• CAS Number: 139346-57-9
• Molecular Weight: 358.35
• Beilstein/REAXYS Number: 5359433
• MDL number: MFCD00467585
• UNSPSC Code: 12352108
• PubChem Substance ID: 57649664
• NACRES: NA.32

Properties

• product line: BioReagent
• assay: ≥96.0% (HPLC)
• solubility: DMF: soluble; DMSO: soluble; acetonitrile: soluble
• fluorescence: λ_ex 445 nm; λ_em 482 nm in 0.1 M phosphate pH 7.0
• suitability: corresponds for coupling to amines; suitable for fluorescence
• storage temp.: −20°C
• SMILES string: CCN(CC)c1ccc2C=C(C(=O)ON3C(=O)CCC3=O)C(=O)Oc2c1
• InChI: 1S/C18H18N2O6/c1-3-19(4-2)12-6-5-11-9-13(17(23)25-14(11)10-12)18(24)26-20-15(21)7-8-16(20)22/h5-6,9-10H,3-4,7-8H2,1-2H3
• InChI key: NUNPVRICKDZFLK-UHFFFAOYSA-N

Description

Application

7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester is used as a reagent to conjugate 7-(diethylamino)coumarin-3-carboxylic acid (7-DCCA) to other molecules such as amino acids via amide chemistry. 7-DCCA is used to label amino acids prior to resolution by capillary zone electrophoresis. 7-DCCA is used as a reference in screening of nerve agent degradation products by MALDI-TOFMS.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Labeling of amino acids prior to resolution by capillary zone electrophoresis

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)