363R-3

PAX-8 (SP348) Rabbit Monoclonal Antibody

• UNSPSC Code: 12352203

Properties

• biological source: rabbit blood
• Quality Level: 500
• conjugate: unconjugated
• antibody form: IgG fraction of tissue culture supernatant
• antibody product type: primary antibodies
• clone: SP348
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL (concentrate (363R-34-RUO) Research Use Only); vial of 0.1 mL ; (concentrate (363R-34)); vial of 0.5 mL (concentrate (363R-35)); vial of 1.0 mL (concentrate (363R-36)); vial of 1.0 mL (concentrate (363R-36-RUO) Research Use Only); vial of 1.0 mL (pre-dilute (363R-37-RUO) Research Use Only); vial of 1.0 mL (pre-dilute ready-to-use (363R-37)); vial of 25.0 mL (pre-dilute ready-to-use (363R-30)); vial of 25.0 mL (pre-dilute ready-to-use (363R-30-RUO)); vial of 7.0 mL (pre-dilute ready-to-use (363R-38)); vial of 7.0 mL (pre-dilute ready-to-use (363R-38-RUO) Research Use Only)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunocytochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:10-1:20 (concentrated))
• isotype: IgG
• control: ovarian carcinoma, papillary carcinoma of thyroid, renal cell carcinoma, (Fallopian Tube)
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear

Description

General description

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidney, and thyroid, with continued expression in neoplastic transformation of some epithelial cell types of these mature tissues.1 It can be useful for marking several types of carcinoma including, but not limited to, ovarian serous carcinoma, clear cell renal cell carcinoma and papillary thyroid carcinoma. Certain anti-PAX-8 antibodies may react with lymphocytes and their neoplasms, which has been attributed to cross-reactivity with PAX-5 due to sequence homology between PAX-8 and PAX-5, but clone SP348 does not exhibit reactivity in these cell types.

Quality

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2