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S5631

Sigma-Aldrich

Silicon dioxide

~99%, 0.5-10 μm (approx. 80% between 1-5 μm)

Synonym(s):

Sand, white quartz, Quartz, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
Molecular Weight:
60.08
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
SB.52

assay

~99%

Quality Level

form

powder

particle size

0.5-10 μm (approx. 80% between 1-5 μm)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Linkage

Historically called amorphous.

Preparation Note

A naturally occurring microcrystalline silica which has been finely ground.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

STOT RE 1 Inhalation

target_organs

Lungs

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shifeng Li et al.
Theranostics, 10(4), 1719-1732 (2020-02-12)
The purpose of this study was to determine the effects of Kinesin family member 3A (KIF3A) on primary cilia and myofibroblast differentiation during silicosis by regulating Sonic hedgehog (SHH) signalling. Methods: Changes in primary cilia during silicosis and myofibroblast differentiation
Alida Kent et al.
Journal of tropical medicine, 2013, 324140-324140 (2013-11-07)
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Outi Leppäranta et al.
American journal of respiratory cell and molecular biology, 48(4), 448-455 (2012-12-22)
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis and very few therapeutic options. On the molecular level, patients with IPF have increased amounts of the bone morphogenetic protein (BMP) inhibitor gremlin in their lungs, which
Haijun Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 310(2), L121-L132 (2015-11-27)
Silicosis is a systemic disease caused by inhaling silicon dioxide (SiO2). Phagocytosis of SiO2 in the lungs initiates an inflammatory cascade that results in fibroblast proliferation and migration followed by fibrosis. According to previous data from our laboratory, monocyte chemotactic
Jian-Feng Li et al.
Plant methods, 6(1), 1-1 (2010-02-26)
Research in plant molecular biology involves DNA purification on a daily basis. Although different commercial kits enable convenient extraction of high-quality DNA from E. coli cells, PCR and agarose gel samples as well as plant tissues, each kit is designed

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