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537551

Sigma-Aldrich

Ethylene glycol butyl ether

≥99%

Synonym(s):

2-Butoxyethanol, Butyl glycol

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About This Item

Linear Formula:
CH3(CH2)3OCH2CH2OH
CAS Number:
111-76-2
Molecular Weight:
118.17
Beilstein/REAXYS Number:
1732511
EC Number:
203-905-0
MDL number:
MFCD00002884
UNSPSC Code:
12352104
PubChem Substance ID:
329757985
NACRES:
NA.21
assay:
≥99%
bp:
169-172.5 °C (lit.)
vapor pressure:
<1 mmHg ( 20 °C)
10 mmHg ( 81 °C)

vapor density

4.1 (vs air)

Quality Level

200

vapor pressure

<1 mmHg ( 20 °C)
10 mmHg ( 81 °C)

assay

≥99%

form

liquid

autoignition temp.

473 °F

expl. lim.

10.6 %

impurities

≤0.10% (water)

refractive index

n20/D 1.419 (lit.)

bp

169-172.5 °C (lit.)

mp

−75 °C (lit.)

solubility

water: soluble

density

0.902 g/mL at 25 °C (lit.)

SMILES string

CCCCOCCO

InChI

1S/C6H14O2/c1-2-3-5-8-6-4-7/h7H,2-6H2,1H3

InChI key

POAOYUHQDCAZBD-UHFFFAOYSA-N

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General description

Ethylene glycol butyl ether (EGBE) is an ethylene oxide-based glycol ether solvent commonly used in the coatings industry. Its relative evaporation rate with respect to n-butyl acetate has been reported to be 0.07. Its toxicity has been assessed. The effect of EGBE as a thickening solvent during acrylic latex synthesis has been investigated.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

152.6 °F - Pensky-Martens closed cup

flash_point_c

67 °C - Pensky-Martens closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
SHBN7554
SHBN6005
SHBN4537
SHBM9576
SHBM7833

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A novel alkali and cosolvent thickening mechanism for latex.
He L, et al.
New. J. Chem., 39(11), 8984-8992 (2015)
Reproductive toxicology. Ethylene glycol monobutyl ether.
Environmental health perspectives, 105 Suppl 1, 217-218 (1997-02-01)
R L Smith
Environmental health perspectives, 57, 1-4 (1984-08-01)
Ethylene oxide-based glycol ether and glycol ether ester solvents have been used in the coatings industry for the past fifty years. Because of their excellent performance properties (evaporation rate, blush resistance, flow-out and leveling properties, solubility for coating resins, solvent
Lisa M Kamendulis et al.
Toxicology, 270(2-3), 131-136 (2010-02-16)
2-Butoxyethanol increases hemangiosarcomas selectively in male mouse liver after chronic inhalation through mechanisms that have not fully been elucidated. Hemolysis, a primary toxic effect associated with 2-butoxyethanol exposure in rodents, increased hemosiderin (iron) deposition in Kupffer cells in the liver.
Annette L Bunge et al.
International journal of pharmaceutics, 435(1), 50-62 (2012-02-15)
Absorption of 2-butoxyethanol (BE) from neat and aqueous solutions of BE was measured through rat skin in vitro and in vivo and through silicone membranes. Like previous studies in human and guinea pig skin, BE flux increased proportional to BE
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