27001

Formic acid

puriss., meets analytical specifications of DAC, FCC, 98.0-100%

• Linear Formula: HCOOH
• CAS Number: 64-18-6
• Molecular Weight: 46.03
• Beilstein/REAXYS Number: 1209246
• EC Number: 200-579-1
• MDL number: MFCD00003297
• UNSPSC Code: 12352106
• PubChem Substance ID: 329752893
• NACRES: NA.21

Properties

• agency: suitable for EPA 1633
• Quality Level: 200
• vapor density: 1.6 (vs air)
• vapor pressure: 44.8 mmHg ( 20 °C)
• grade: puriss.
• assay: 98.0-100%
• form: liquid
• autoignition temp.: 1004 °F
• quality: meets analytical specifications of DAC, FCC
• expl. lim.: 57 %
• technique(s): HPLC: suitable
• impurities: ≤0.001% heavy metals (as Pb); ≤0.005% non-volatile matter; ≤0.05% acetic acid (GC)
• refractive index: n20/D 1.370 (lit.)
• pH: 2.2 (20 °C, 2.2 g/L)
• bp: 100-101 °C (lit.)
• mp: 8.2-8.4 °C (lit.)
• density: 1.22 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤10 mg/kg; sulfate (SO₄^2-): ≤40 mg/kg; sulfite (SO₃^2-): ≤50 mg/kg
• cation traces: Fe: ≤0.001%; heavy metals (as Pb): ≤0.001%
• SMILES string: OC=O
• InChI: 1S/CH2O2/c2-1-3/h1H,(H,2,3)
• InChI key: BDAGIHXWWSANSR-UHFFFAOYSA-N

Description

Application

• Evaluation of aloins, pH and moisture in aloe leaf gel-based personal care products.: This research assessed the consistency and quality of aloe-based products using advanced analytical chemistry techniques, including formic acid in sample preparation to stabilize pH levels and enhance detection accuracy (Sibhat et al., 2022).


• Multi-Residue Analysis of Fipronil and Its Metabolites in Eggs by SinChERS-Based UHPLC-MS/MS.: Describes the use of formic acid in the sample preparation phase to improve the extraction and detection of pesticide residues, demonstrating its pivotal role in ensuring food safety (Han et al., 2021).


• Simultaneous determination of phenolic acids and flavonoids in Artemisiae Argyi Folium by HPLC-MS/MS and discovery of antioxidant ingredients based on relevance analysis.: Illustrates how formic acid was essential for modifying the mobile phase in chromatography, enhancing the resolution and quantification of bioactive compounds (Xia et al., 2019).


• Evaluation of three different artificial agarwood-inducing methods from Aquilaria sinensis using antimicrobial activity.: This study used formic acid in antimicrobial assays to compare the efficacy of different agarwood induction techniques, highlighting its versatility in bioactive compound analysis (Lei et al., 2019).


• Chemical Analysis and Multi-Component Determination in Chinese Medicine Preparation Bupi Yishen Formula Using Ultra-High Performance Liquid Chromatography With Linear Ion Trap-Orbitrap Mass Spectrometry and Triple-Quadrupole Tandem Mass Spectrometry.: Showcases the application of formic acid in the complex analysis of traditional Chinese medicine, enabling precise quantification and identification of multiple components simultaneously (Zhang et al., 2018).

Other Notes

The article number 27001-4X2.5L-M will be discontinued. Please order the single bottle 27001-2.5L-M which is physically identical with the same exact specifications.
The article number 27001-4X2.5L-R will be discontinued. Please order the single bottle 27001-2.5L-R which is physically identical with the same exact specifications.
The article number 27001-6X1L-R will be discontinued. Please order the single bottle 27001-1L-R which is physically identical with the same exact specifications.

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H226,H302,H314,H331
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
• supp_hazards: EUH071
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 118.4 °F - closed cup
• flash_point_c: 48 °C - closed cup