208566

Titanium(IV) chloride

ReagentPlus^®, 99.9% trace metals basis

• Synonym(s): TTC, Titanium tetrachloride
• Linear Formula: TiCl₄
• CAS Number: 7550-45-0
• Molecular Weight: 189.68
• EC Number: 231-444-5
• MDL number: MFCD00011267
• UNSPSC Code: 12352300
• PubChem Substance ID: 329752044
• NACRES: NA.55

Properties

• vapor pressure: 50 mmHg ( 55 °C); 9.6 mmHg ( 20 °C)
• Quality Level: 100; 200
• product line: ReagentPlus^®
• assay: 99.9% trace metals basis
• form: liquid
• reaction suitability: reagent type: catalyst; core: titanium
• bp: 135-136 °C (lit.)
• mp: −25 °C (lit.)
• density: 1.73 g/mL at 20 °C (lit.)
• SMILES string: Cl[Ti](Cl)(Cl)Cl
• InChI: 1S/4ClH.Ti/h4*1H;/q;;;;+4/p-4
• InChI key: XJDNKRIXUMDJCW-UHFFFAOYSA-J

Description

General description

Titanium(IV) chloride participates in the Baylis-Hillman reaction of arylaldehydes with methyl vinyl ketone. Neutral solutions of TiCl₄ having a pH in the range of 2.5 to 6.0 (prepared by the addition of magnesium oxide as a base) have been used for the synthesis of nanosized titanium dioxide.

Application

Activates pyrrolidines for improved conversion, via a modified Bouveault reaction, to the corresponding α,α-dimethylamines.

Along with sodium borohydride, it forms an effective reagent for the reduction of:

• carboxylic acid and acyl chloride to alcohols
• carboxamides, oximes and lactams to amines
• sulfoxides to sulfides

Titanium(IV) chloride (TiCl₄) has been used as a precursor for the synthesis of Ag-TiO₂@polyethylene glycol (PEG) nanoparticles. TiCl₄ may also be used as one of the constituents to synthesize TiO₂/Al₂O₃ binary oxide materials and N-(10-oxo-vinylanthracen-9-(10H)-ylidene)cyanamide.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H314,H330,H335
• pcodes: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014
• Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable