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Y0001410

Sodium fusidate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Fusidic acid sodium salt, Fucidin

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About This Item

Linear Formula:
C31H47O6Na
CAS Number:
751-94-0
Molecular Weight:
538.69
MDL number:
MFCD09054714
UNSPSC Code:
41116107
PubChem Substance ID:
329831410
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

sodium fusidate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].C[C@@H]1[C@H](O)CC[C@@]2(C)C1CC[C@@]3(C)C2[C@H](O)CC4\C([C@H](C[C@]34C)OC(C)=O)=C(/CC\C=C(\C)C)C([O-])=O

InChI

1S/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

InChI key

HJHVQCXHVMGZNC-JCJNLNMISA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sodium fusidate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Topical antibiotics in the treatment of superficial skin infections in general practice?a comparison of mupirocin with sodium fusidate.
White D G, et al.
The Journal of Infection, 18(3), 221-229 (1989)
Determination of fusidic acid and sodium fusidate in pharmaceutical dosage forms by first-derivative ultraviolet spectrophotometry.
Hassan S M, et al.
Analyst, 112(10), 1459-1461 (1987)
Saleem Shaikh et al.
Journal of chromatographic science, 47(2), 178-183 (2009-02-19)
A simple, specific, and precise high-performance liquid chromatographic method is developed and validated for the simultaneous determination of chlorocresol (CC), mometasone furoate (MF), and fusidic acid (FA) in a cream formulation. The isocratic mobile phase consists of 1.5% w/v aqueous
Katharina Wittmann et al.
Tissue engineering. Part A, 21(7-8), 1343-1353 (2015-01-21)
The development of vascularized and functional adipose tissue substitutes is required to improve soft tissue augmentation. In this study, vascularized adipose tissue constructs were generated using uncultured cells from the stromal-vascular fraction (SVF) of adipose tissue as an alternative cell

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