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PHR2716

Supelco

Imiquimod

Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500 mg

Synonym(s):
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
Empirical Formula (Hill Notation):
C14H16N4
CAS Number:
Molecular Weight:
240.30
MDL number:

grade

certified reference material
pharmaceutical secondary standard

Agency

traceable to USP 1338313

API family

imiquimod

form

solid

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

storage temp.

2-30°C

SMILES string

CC(C)Cn1cnc2c(N)nc3ccccc3c12

InChI

1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

InChI key

DOUYETYNHWVLEO-UHFFFAOYSA-N

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This Item
PHR2489PHR2490PHR3014
Imiquimod Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500 mg

Supelco

PHR2716

Imiquimod

form

solid

form

solid

form

solid

form

-

agency

traceable to USP 1338313

agency

traceable to USP 1338324

agency

traceable to USP 1338346

agency

traceable to USP 1338335

API family

imiquimod

API family

imiquimod

API family

imiquimod

API family

imiquimod

CofA

current certificate can be downloaded

CofA

-

CofA

-

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

packaging

pkg of 50 mg

packaging

pkg of 50 mg

packaging

pkg of 50 mg

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biochem/physiol Actions

Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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