PHR2082

Pyrantel Impurity B

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): (E)-N-[3-(Methylamino)propyl]-3-thiophen-2-yl)prop-2-enamide hydrochloride
• Empirical Formula (Hill Notation): C₁₁H₁₆N₂OS · HCl
• CAS Number: 36700-39-7
• Molecular Weight: 260.78
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• API family: pyrantel
• CofA: current certificate can be downloaded
• packaging: pkg of 50 mg
• application(s): pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• InChI: 1S/C11H16N2OS/c1-12-7-3-8-13-11(14)6-5-10-4-2-9-15-10/h2,4-6,9,12H,3,7-8H2,1H3,(H,13,14)/b6-5+
• InChI key: NQKWXBJGZHHURS-AATRIKPKSA-N

Description

General description

Pyrantel Impurity B is an impurity of the broad-spectrum anthelminthic drug, pyrantel. Pyrantel is a medication, commonly indicated for the treatment of intestinal nematodes. Its mode of action involves the interference with ganglionic neurotransmission via blocking of the acetylcholine receptors and other sites, which in turn leads to paralysis of the parasites.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB9057 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable