PHR1681

Supelco

Benzalkonium Chloride 50% Solution

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Alkylbenzyldimethylammonium chloride, Benzalkonium chloride solution
CAS Number:
MDL number:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

Featured Industry

Pharmaceutical (small molecule)

format

single component solution

pharmacopeia traceability

traceable to PhEur Y0001060
traceable to USP 1050993

InChI

1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1

InChI key

TTZLKXKJIMOHHG-UHFFFAOYSA-M

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzalkonium chloride is an antimicrobial preservative and is widely used against Gram-positive and Gram-negative organisms. It finds applications in cosmetic industry and pharmaceutical formulations.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2095 in the slot below. This is an example certificate only and may not be the lot that you receive.

Signal Word

Danger

Hazard Statements

hazcat

Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B

storage_class_code

8A - Combustible, corrosive hazardous materials

WGK Germany

WGK 2

Certificate of Analysis

Certificate of Origin

CRC Handbook of Food, Drug, and Cosmetic Excipients (1992)
Rapid determination of total benzalkonium chloride content in ophthalmic formulation.
Labranche P-L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 989-993 (2007)

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