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Pharmaceutical Secondary Standard; Certified Reference Material

BHA, 3-BHA, 2-tert-Butyl-4-methoxyphenol
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


certified reference material
pharmaceutical secondary standard


traceable to USP 1083100


current certificate can be downloaded


HPLC: suitable
gas chromatography (GC): suitable


pharmaceutical (small molecule)



storage temp.


SMILES string




InChI key


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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
3-tert-Butyl-4-hydroxyanisole is a synthetic antioxidant, widely used as a food additive to prevent oxidative deterioration of fats and oils.


3-tert-Butyl-4-hydroxyanisole may be used as a pharmaceutical reference standard for the determination of the analyte in plasma samples using high-resolution capillary gas chromatography-mass spectrometry with selective ion monitoring.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


To see an example of a Certificate of Analysis for this material enter LRAA0066 in the slot below. This is an example certificate only and may not be the lot that you receive.


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Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

Determination of the antioxidant 3-tert.-butyl-4-hydroxyanisole in rat plasma using high-resolution gas chromatography?mass spectrometry
Bailey E, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 225(1), 83-89 (1981)
Nathalie Allaman-Pillet et al.
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Hye Jin Jung et al.
PloS one, 9(11), e112256-e112256 (2014-11-15)
Silver materials have been widely used in diverse fields. However, their toxicity and their mechanism, especially in different forms, have not been studied sufficiently. Thus, cytotoxicity, apoptosis, and interleukin-1beta (IL-1β) production were investigated using macrophage-like THP-1 cells in the presence
Huilin Liu et al.
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