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Isopropyl myristate

Pharmaceutical Secondary Standard; Certified Reference Material

Myristic acid isopropyl ester, IPM 100, IPM, IPM-R, Isopropyl tetradecanoate, IPM-EX
Linear Formula:
CAS Number:
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EC Number:
MDL number:
PubChem Substance ID:

Quality Level


certified reference material
pharmaceutical secondary standard


traceable to Ph. Eur. I0750000
traceable to USP 1350400


current certificate can be downloaded


HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.434 (lit.)


193 °C/20 mmHg (lit.)


~3 °C (lit.)


0.85 g/mL at 25 °C (lit.)


cleaning products
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)



storage temp.


SMILES string




InChI key


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General description

Isopropyl myristate is an ester of isopropyl alcohol myristic acid. It is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It also finds applications as a flavoring agent in the food industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.


These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


To see an example of a Certificate of Analysis for this material enter LRAA7001 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

10 - Combustible liquids



Flash Point(F)

305.6 °F - closed cup

Flash Point(C)

152 °C - closed cup

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

CRC Handbook of Food, Drug, and Cosmetic Excipients (1992)
Vinécius Raphael de Almeida Borges et al.
International journal of nanomedicine, 8, 535-544 (2013-02-16)
Topical administration of dapsone can be an alternative route for treatment of leprosy and can also provide new therapeutic applications for an established drug. However, the physicochemical properties of dapsone make it difficult to incorporate into conventional formulations. The current
Fahima M Hashem et al.
AAPS PharmSciTech, 12(3), 879-886 (2011-07-05)
The objective of the present study was to formulate and evaluate microemulsion systems for topical delivery of clotrimazole (CTM). The solubility of CTM in various oils was determined to select the oil phase of the microemulsion systems. Pseudoternary phase diagrams
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate

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