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Key Documents

PHL89716

Indirubin

phyproof® Reference Substance

Synonym(s):

Coroupitine B, Indigo Red, Indigopurpurin

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About This Item

Empirical Formula (Hill Notation):
C16H10N2O2
CAS Number:
Molecular Weight:
262.26
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥95.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

storage temp.

−20°C

InChI

1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13+

InChI key

CRDNMYFJWFXOCH-BUHFOSPRSA-N

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application


  • Indirubin for leukemia treatment: Indirubin′s role as a kinase inhibitor positions it as a potential therapeutic in leukemia treatment. Its inhibition of cyclin-dependent kinases suggests utility in cell cycle regulation, which is pivotal in leukemia pathology. Research highlights its capabilities to modulate kinase activity, providing a pathway to targeted cancer therapies (Wang et al., 2024).

  • Indirubin in cancer research: As an anti-cancer agent, Indirubin demonstrates efficacy in vitro, particularly in inducing apoptosis in cancer cells. Its interaction with cellular signaling pathways enhances its potential as a therapeutic agent in various cancers, underlining its importance in oncological studies (Li et al., 2024).

  • Indirubin for neurodegenerative disease study: Exploring Indirubin′s effects on neurodegenerative diseases, recent studies focus on its neuroprotective properties through the regulation of kinase signaling pathways. This research underpins its therapeutic potential in diseases like Alzheimer′s and Parkinson′s, indicating its broad applicability in neurology (Li et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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