I0800000
Isotretinoin
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
13-cis-Retinoic acid, Isotretinoin
About This Item
Recommended Products
biological source
synthetic
grade
pharmaceutical primary standard
agency
EP
API family
isotretinoin
form
solid
manufacturer/tradename
EDQM
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
mp
172-175 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
[H]\C(C(O)=O)=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
InChI
1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChI key
SHGAZHPCJJPHSC-XFYACQKRSA-N
Gene Information
human ... RARA(5914) , RARB(5915) , RARG(5916)
Looking for similar products? Visit Product Comparison Guide
General description
Isotretinoin, a vital isomer of vitamin A, is implicated in the treatment of severe recalcitrant nodular acne disorder. It is the only drug known to operate against the major pathogenic factors of acne. It serves to diminish the sebaceous gland activity, thereby resulting in the correction of keratinization defect.
Application
Biochem/physiol Actions
Packaging
Other Notes
Related product
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Sorry, we don't have COAs for this product available online at this time.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service