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D2954000

Dobutamine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C18H23NO3 · HCl
CAS Number:
49745-95-1
Molecular Weight:
337.84
MDL number:
MFCD00153795
UNSPSC Code:
41116107
PubChem Substance ID:
329798764
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dobutamine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2

InChI

1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

InChI key

BQKADKWNRWCIJL-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153) , ADRB2(154)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dobutamine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Journal of the American Heart Association, 2(2), e000097-e000097 (2013-04-18)
Patients with a myocardial bridge (MB) and no significant obstructive coronary artery disease (CAD) may experience angina presumably from ischemia, but noninvasive assessment has been limited and the underlying mechanism poorly understood. This study seeks to correlate a novel exercise
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Circulation research, 114(1), 109-113 (2013-10-22)
Microparticles are cell-derived membrane vesicles, relevant to a range of biological responses and known to be elevated in cardiovascular disease. To investigate microparticle release during cardiac stress and how this response differs in those with vascular disease. We measured a
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Circulation. Cardiovascular imaging, 6(2), 268-276 (2013-01-01)
Decision making in patients with low flow-low gradient aortic stenosis mainly depends on the actual stenosis severity and left ventricular function, which is of prognostic importance. We used 2-dimensional strain parameters measured by speckle tracking at rest and during dobutamine
E Bartha et al.
British journal of anaesthesia, 110(4), 545-553 (2013-01-01)
Patients with proximal femoral fracture (PFF) are at high risk of postoperative complications. Goal-directed haemodynamic treatment (GDHT) in other high-risk surgical patients reduces postoperative complications. We aimed to compare effects of GDHT and routine fluid treatment (RFT) on postoperative outcomes
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