83300

2-Pyrrolidinone

purum, ≥98.0% (GC)

• Synonym(s): 2-Pyrrolidone, Butyrolactam
• Empirical Formula (Hill Notation): C₄H₇NO
• CAS Number: 616-45-5
• Molecular Weight: 85.10
• Beilstein/REAXYS Number: 105241
• EC Number: 210-483-1
• MDL number: MFCD00005270
• UNSPSC Code: 12352100
• PubChem Substance ID: 329769287
• NACRES: NA.22

Properties

• vapor density: 2.9 (vs air)
• Quality Level: 200
• grade: purum
• assay: ≥98.0% (GC)
• form: solid
• refractive index: n20/D 1.487 (lit.)
• bp: 245 °C (lit.)
• mp: 23-25 °C (lit.)
• solubility: H₂O: miscible (completely)
• density: 1.12 g/mL at 25 °C (lit.)
• SMILES string: O=C1CCCN1
• InChI: 1S/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6)
• InChI key: HNJBEVLQSNELDL-UHFFFAOYSA-N
• Gene Information: rat ... Gabra2(29706)

Description

Application

• 2-Pyrrolidinone is used in the synthesis of N-vinylpyrrolidone, from which polyvinylpyrrolidone (PVP) is obtained.
• It can be used as a ligand in the preparation of one-dimensional coordination polymers and mixed transition metal-lanthanide complexes.
• 1,2-amino alcohols can be reacted with carbon dioxide in the presence of 2-pyrrolidinone electrogenerated base to synthesize various oxazolidin-2-ones (Evans-type auxiliaries).
• It is a key starting material in the synthesis of (±)-tetraponerine T4.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H319,H360D
• pcodes: P201 - P202 - P264 - P280 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type N95 (US)