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74886

Supelco

Sodium 1-octanesulfonate solution

suitable for ion pair chromatography, LiChropur™, concentrate, ampule

Synonym(s):

1-Octanesulfonic acid sodium salt

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About This Item

Linear Formula:
CH3(CH2)6CH2SO3Na
CAS Number:
5324-84-5
Molecular Weight:
216.27
Beilstein/REAXYS Number:
3574241
MDL number:
MFCD00007544
UNSPSC Code:
12000000
PubChem Substance ID:
329765940
NACRES:
NB.21

Quality Level

100

form

liquid

quality

LiChropur™
ampule

packaging

ampule of 25 mL

technique(s)

ion pair chromatography: suitable

λ

in concentrate

UV absorption

λ: 210 nm Amax: 0.08
λ: 220 nm Amax: 0.05
λ: 230 nm Amax: 0.03
λ: 260 nm Amax: 0.02
λ: 500 nm Amax: 0.02

suitability

corresponds to standard for RP gradient test
corresponds to standard for filter test

SMILES string

[Na+].CCCCCCCCS([O-])(=O)=O

InChI

1S/C8H18O3S.Na/c1-2-3-4-5-6-7-8-12(9,10)11;/h2-8H2,1H3,(H,9,10,11);/q;+1/p-1

InChI key

HRQDCDQDOPSGBR-UHFFFAOYSA-M

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General description

Concentrate for 6x1 L ready-to-use solution. Dilute contents of one ampule (~0.3 M) to 1 L with HPLC grade water to obtain a 0.005 M eluent solution.
Sodium 1-octanesulfonate monohydrate (NaOS) is an ion-pairing reagent.

Application

NaOS has been used as ion-pairing reagent for ultra-high performance liquid chromatography (UPLC) analysis with photodiode array detection to estimate paraquat (methyl viologen) in tissue homogenate. It may also be used in determination of dopamine and its metabolites in brain microdialysates using liquid chromatography combined with electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS).

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF8165
BCCC8099
BCBW2039
BCBV1413
BCBR7899V

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Rapid and simple analysis of paraquat in tissue homogenate by ultra-high performance liquid chromatography.
Merritt, T. J. S., et al.
Analytical Methods : Advancing Methods and Applications, 3.6, 1428-1432 (2011)
Kamila Syslová et al.
Journal of chromatography. A, 1218(21), 3382-3391 (2011-03-15)
A sensitive assay method was developed for a parallel, rapid and precise determination of dopamine and its metabolites, homovanillic acid, 3-methoxytyramine and 3,4-dihydroxyphenylacetic acid, from brain microdialysates. The method consisted of a pre-treatment step, freeze-drying (lyophilization), to concentrate dopamine and
Can Zhang et al.
Biomaterials, 29(9), 1233-1241 (2007-12-21)
Paclitaxel (Taxol), PTX) is a promising anti-cancer drug and has been successfully used to treat a wide variety of cancers. Unfortunately, serious clinical side effects are associated with it, which are caused by PTX itself and non-aqueous vehicle containing Cremophor
J G Foulks et al.
Canadian journal of physiology and pharmacology, 63(10), 1327-1334 (1985-10-01)
The potency of various types of alkyl amphipathic (cationic, anionic, and neutral) as well as tertiary amine local anesthetics in impairing the excitability of frog skeletal muscle was markedly enhanced by an increase in temperature from 20 to 30 degrees
H T Jung et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(4), 1353-1357 (2001-02-15)
Equilibrium unilamellar vesicles are stabilized by one of two distinct mechanisms depending on the value of the bending constant. Helfrich undulations ensure that the interbilayer potential is always repulsive when the bending constant, K, is of order k(B)T. When K
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