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69532

Supelco

Artemisinin

analytical standard

Synonym(s):

Arteannuin, Qinghaosu

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About This Item

Empirical Formula (Hill Notation):
C15H22O5
CAS Number:
63968-64-9
Molecular Weight:
282.33
MDL number:
MFCD00081057
UNSPSC Code:
41116107
PubChem Substance ID:
329761732
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98.0% (TLC)

optical activity

[α]/D +75.0±3°, c = 0.5 in methanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

156-157 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4

InChI

1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

InChI key

BLUAFEHZUWYNDE-NNWCWBAJSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF6312
BCCD7493
BCCC8187
BCCB8373
BCBW9378

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Benjamin J Visser et al.
Expert opinion on pharmacotherapy, 15(15), 2219-2254 (2014-08-12)
Chemotherapy of malaria has become a rapidly changing field. Less than two decades ago, treatment regimens were increasingly bound to fail due to emerging drug resistance against 4-aminoquinolines and sulfa compounds. By now, artemisinin-based combination therapies (ACTs) constitute the standard
Victor M Ye et al.
Biotechnology journal, 7(1), 20-33 (2011-10-25)
Driven by requirements for sustainability as well as affordability and efficiency, metabolic engineering of plants and microorganisms is increasingly being pursued to produce compounds for clinical applications. This review discusses three such examples of the clinical relevance of metabolic engineering:
Ambrose O Talisuna et al.
The Lancet. Infectious diseases, 12(11), 888-896 (2012-10-27)
Artemisinin-resistant Plasmodium falciparum malaria has emerged in western Cambodia and has been detected in western Thailand. The situation is ominously reminiscent of the emergence of resistance to chloroquine and to sulfadoxine-pyrimethamine several decades ago. Artemisinin resistance is a major threat
Pamela J Weathers et al.
Journal of ethnopharmacology, 153(3), 732-736 (2014-03-26)
The Chinese have used Artemisia annua as a tea infusion to treat fever for >2000 years. The active component is artemisinin. Previously we showed that when compared to mice fed an equal amount of pure artemisinin, a single oral dose
C Wongsrichanalai et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 19(10), 908-916 (2013-09-17)
Following a decade-long scale up of malaria control through vector control interventions, the introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination Therapy (ACT) along with other measures, global malaria incidence declined significantly. The recent development of artemisinin resistance
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