46802

Sulfamethazine

VETRANAL^®, analytical standard

• Synonym(s): 4,6-Dimethylsulfadiazine, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, Sulfadimethyldiazine, Sulfadimidine
• Empirical Formula (Hill Notation): C₁₂H₁₄N₄O₂S
• CAS Number: 57-68-1
• Molecular Weight: 278.33
• Beilstein: 261304
• EC Number: 200-346-4
• MDL number: MFCD00006066
• PubChem Substance ID: 329757245
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 200
• Agency: EPA 1694
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• application(s): clinical testing
• format: neat
• Mode of action: DNA synthesis | interferes; enzyme | inhibits
• SMILES string: Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
• InChI: 1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
• InChI key: ASWVTGNCAZCNNR-UHFFFAOYSA-N

Description

General description

Chemical structure: sulfonamide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

An antimicrobial sulfur drug. Induces CYP3A4 expression and acetylated by N-acetyltransferase. Exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves