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439223

Sigma-Aldrich

Dichloromethane

suitable for HPLC, ≥99.9%, contains 40-150 ppm amylene as stabilizer

Synonym(s):

Methylene chloride

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About This Item

Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
Beilstein/REAXYS Number:
1730800
EC Number:
MDL number:
UNSPSC Code:
12190000
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.9 (vs air)

Quality Level

vapor pressure

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

1223 °F

contains

40-150 ppm amylene as stabilizer

expl. lim.

22 %

technique(s)

HPLC: suitable

impurities

Free halogens, passes test
≤0.0003 meq/g Titr. acid
≤0.02% water

evapn. residue

<0.0003%

color

APHA: ≤10
clear

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 235 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 250 nm Amax: 0.05
λ: 260 nm Amax: 0.02
λ: 340-400 nm Amax: 0.01

suitability

passes test for HPLC

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

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General description

Dichloromethane (DCM) is a chlorinated organic solvent with a wide range of industrial applications. It has C2v symmetry, low boiling point, high density and is immiscible in water. Degradation of DCM by various methods has been reported. Ultrasonic absorption studies of liquid DCM shows strong relaxation effect. A study reports the dielectric characteristics of DCM over a wide frequency range. DCM is susceptible to degradation with time, which can be suppressed by adding amylene as a stabilizer.

Application

Dichloromethane (Methylene chloride) may be used in the following processes:
  • To compose ultrasonic baths for cleaning and protection of aluminum coating over atactic-PMMA (poly(methyl methacrylate)) for dielectric studies.
  • Preparation of AMBF3 (ammoniomethyltrifluoroborate)-conjugated biomolecules.
  • Sample preparation for GC-MS (Gas Chromatography-Mass Spectrometry) analysis.
  • Preparation of ammonium acetate solvent mixture in combination with isopropanol, acetonitrile and water for mass spectral analysis of neutral lipids.
  • Quantification of glutathione (GSH) and glutathione disulfide (GSSG) in biological samples by HPLC and spectrophotometry.
  • As an extractant for 2,2-dithioethyl-4-(2′-pyridyl)-4-butyro-γ-lactone.
Meets ACS specifications

Preparation Note

Product filtered through a 0.2 μm filter

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash

ppe

Eyeshields, Faceshields, Gloves


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