43623

Supelco

β-Sitosterol

analytical standard

Synonym(s):
22,23-Dihydrostigmasterol, 5-Stigmasten-3β-ol, α-Dihydrofucosterol, 24α-Ethylcholesterol
Empirical Formula (Hill Notation):
C29H50O
CAS Number:
Molecular Weight:
414.71
Beilstein/REAXYS Number:
1916165
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

assay

≥90.0% (GC)

form

neat

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤10.0% water

mp

136-140 °C (lit.)

Featured Industry

Food and Beverages

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CC[C@@H](CC)C(C)C

InChI

1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChI key

KZJWDPNRJALLNS-VJSFXXLFSA-N

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General description

beta-Sitosterol is the most abundant phytosterol, which can serve as a potential and promising candidate in the treatment of tumor and breast cancer, via suppressing the tumor and cancer cell growth.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
beta-Sitosterol has been used as an analytical standard in the determination of free sterols or oxysterols in food matrices, using gas chromatography and ion trap mass spectrometry (GC-MS).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

?-Sitosterol activates Fas signaling in human breast cancer cells
Awad.B.A, et al.
Phytomedicine, 14, 747-754 (2007)
New method to determine free sterols/oxysterols in food matrices using gas chromatography and ion trap mass spectrometry (GC?IT-MS)
Szterk A and Pakula L
Talanta, 152, 54-75 (2016)
Günther Silbernagel et al.
Current opinion in lipidology, 24(1), 12-17 (2012-11-21)
Plant sterols as ingredients to functional foods are recommended for lowering LDL cholesterol. However, there is an ongoing discussion whether the use of plant sterols is safe. Genetic analyses showed that common variants of the ATP binding cassette transporter G8...
Ashutosh Singh
Food chemistry, 137(1-4), 62-67 (2012-12-04)
The antioxidative effect of sitosterol at 1, 2 and 5% levels, in triolein, refined canola, high oleic sunflower and flaxseed oils, continuously heated for a period of up to 72 h at frying temperature of 180 °C, was studied. High...
Katarzyna Hąc-Wydro
Colloids and surfaces. B, Biointerfaces, 110, 113-119 (2013-05-29)
In this paper the influence of one of phytosterols, namely β-sitosterol on cholesterol (Chol)/phosphatidylcholine (PC)/ganglioside (GM3) monolayers was examined to find the correlation between the properties of model system and the effect of phytocompound. The studied monolayers differed in condensation...

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