38907

Isorhamnetin

analytical standard

• Synonym(s): 3′-Methoxy-3,4′,5,7-tetrahydroxyflavone, 3′-Methylquercetin, 3,4′,5,7-Tetrahydroxy 3′-methoxyflavone, Isorhamnetol, Quercetin 3′-methyl ether
• Empirical Formula (Hill Notation): C₁₆H₁₂O₇
• CAS Number: 480-19-3
• Molecular Weight: 316.26
• Beilstein/REAXYS Number: 44723
• EC Number: 207-545-5
• MDL number: MFCD00017310
• UNSPSC Code: 85151701
• PubChem Substance ID: 329755802
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥99% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): food and beverages
• format: neat
• storage temp.: 2-8°C
• SMILES string: COc1cc(ccc1O)C2=C(O)C(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C16H12O7/c1-22-11-4-7(2-3-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3
• InChI key: IZQSVPBOUDKVDZ-UHFFFAOYSA-N

Description

General description

Isorhamnetin belongs to the flavonoids class of compounds.

Application

Isorhamnetin may be used as an analytical reference standard for the determination of isorhamnetin in:

• Rat plasma samples by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
• Lotus (Nelumbo nucifera) leaves by macroporous resin chromatography combined with HPLC-ESI-MS/MS.
• Powdered extracts and finished products samples of Ginkgo biloba by HPLC-MS.
• Human plasma and urine by high-throughput micro solid-phase extraction (μ-SPE), followed by analysis using UHPLC in interface with quadrupole time-of-flight mass spectrometry (Q TOFMS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Isorhamnetin inhibits adipogenesis by interfering with differentiation of adipose stem cells, by a mechanism involving stabilization of β-catenin and up-regulating the Wnt signaling pathway.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: ginkgo glycyrrhiza primula

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable