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32407

Supelco

Cymiazole

PESTANAL®, analytical standard

Synonym(s):

2,4-Dimethyl-N-(3-methyl-2(3H)-thiazolylidene)benzenamine, 2-(2,4-Dimethylphenylimino)-3-methylthiazoline, 2-(2,4-Xylylimino)-3-methylthiazoline, N-[(2EZ)-3-Methyl-1,3-thiazol-2-(3H)ylidene]-2,4-xylidine

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About This Item

Empirical Formula (Hill Notation):
C12H14N2S
CAS Number:
61676-87-7
Molecular Weight:
218.32
Beilstein/REAXYS Number:
1213211
EC Number:
262-890-9
MDL number:
MFCD01311800
UNSPSC Code:
41116107
PubChem Substance ID:
329754188
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CN1C=CSC1=Nc2ccc(C)cc2C

InChI

1S/C12H14N2S/c1-9-4-5-11(10(2)8-9)13-12-14(3)6-7-15-12/h4-8H,1-3H3/b13-12-

InChI key

YUAUPYJCVKNAEC-SEYXRHQNSA-N

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Application

Cymiazole may be used as an analytical reference standard for the determination of the analyte in honey, royal jelly and beeswax by modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) method coupled with LC-MS/MS (liquid chromatography tandem mass spectrometry) and solid phase extraction (SPE), followed by gas chromatography-mass spectrometry (GC-MS) analysis, respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ1915
BCCB6672
BCBW0580
BCBV1398
SZBE035XV

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P Cabras et al.
Journal of AOAC International, 76(1), 92-94 (1993-01-01)
A liquid chromatographic method is described for the determination of cymiazole residues in honey. This acaricide is determined on a reversed-phase (C18) column, with a CH3CN-0.001N HCl-NaCl mixture (950 mL + 50 mL + 0.3 g/L) as the mobile phase
Zoran Stanimirovic et al.
Mutation research, 588(2), 152-157 (2005-11-29)
Apitol, with cymiazole hydrochloride as the active ingredient, is used in bee-keeping against the ectoparasitic mite Varroa destructor. The preparation was evaluated for genotoxicity in cultured human peripheral blood lymphocytes. Sister chromatid exchange, the mitotic index and the cell proliferation
U Kryger et al.
Bulletin of entomological research, 96(6), 597-603 (2007-01-05)
In a bioassay to determine non-target ecotoxicological effects of a pyrethroid spray (Ektoban) on dung beetles, dung from both cypermethrin/cymiazol-treated and control cattle was collected one, two, three, five, seven, 14, 21 and 28 days after treatment and fed to
Development and validation of modified QuEChERS method coupled with LC--MS/MS for simultaneous determination of cymiazole, fipronil, coumaphos, fluvalinate, amitraz, and its metabolite in various types of honey and royal jelly.
Zheng W, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1072, 60-69 (2018)
Determination of amitraz and other acaricide residues in beeswax.
Korta E, et al.
Analytica Chimica Acta, 475(1-2), 97-103 (2003)

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