30552

Monensin methyl ester

Selectophore^™, ≥97.0% (TLC)

• Synonym(s): Methyl monensin
• Empirical Formula (Hill Notation): C₃₇H₆₄O₁₁
• CAS Number: 28636-21-7
• Molecular Weight: 684.90
• Beilstein/REAXYS Number: 3641733
• UNSPSC Code: 26111700
• NACRES: NB.61

Properties

• grade: for ion-selective electrodes
• Quality Level: 200
• product line: Selectophore^™
• assay: ≥97.0% (TLC)
• storage temp.: 2-8°C
• SMILES string: CC[C@]1(CCC(O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)C(O3)[C@@H](C)[C@@H](OC)[C@H](C)C(=O)OC)O2)C4OC(C[C@@H]4C)C5O[C@@](O)(CO)[C@H](C)C[C@@H]5C
• InChI: 1S/C37H64O11/c1-11-35(32-21(3)17-27(44-32)29-20(2)16-22(4)37(41,19-38)47-29)13-12-28(45-35)34(8)14-15-36(48-34)18-26(39)23(5)31(46-36)24(6)30(42-9)25(7)33(40)43-10/h20-32,38-39,41H,11-19H2,1-10H3/t20-,21+,22+,23+,24+,25+,26-,27-,28+,29-,30-,31-,32-,34+,35-,36+,37-/m0/s1
• InChI key: PFRZSHIENRKVSE-RJTHVKINSA-N

Description

General description

Monensin, is an antibiotic produced by Streptomyces cinnamonensis. It is a naturally occurring ionophore. It has an acyclic polyether sequence and a terminal carboxylic acid moiety. It has the ability to effectively carry protons and cations through the cell membrane, hence it adequately harbours Na⁺ into a characteristic pseudoactivity, thereby effectively transporting it across a bio-membrane. It also forms stable complexes with k⁺, Rb⁺ and Ag⁺; hence it can be chemically modified to form cation-binding sites, thereby attaining transport functionalities.

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Application

• The selectivity of membrane ion-selective electrodes: This research explores the use of temperature variations to adjust the selectivity of ion-selective electrodes, utilizing Monensin methyl ester as a key component for sodium ion detection (Zahran et al., 2010).


• Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.: This paper presents a detailed analysis of the proton channel properties of Monensin methyl ester through spectroscopic and computational methods, highlighting its potential in analytical chemistry applications (Huczyński et al., 2006).


• Ion chromatography detector based on solid-state ion-selective electrode array.: The development of an ion chromatography detector employing solid-state ion-selective electrodes, with Monensin methyl ester playing a crucial role in sodium ion detection, is detailed in this study (Lee et al., 2000).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges