05360590

Genistein

primary reference standard

• Synonym(s): 4′,5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• Empirical Formula (Hill Notation): C₁₅H₁₀O₅
• CAS Number: 446-72-0
• Molecular Weight: 270.24
• Beilstein/REAXYS Number: 263823
• EC Number: 207-174-9
• MDL number: MFCD00016952
• UNSPSC Code: 41116107
• PubChem Substance ID: 329747700
• NACRES: NA.24

Properties

• grade: primary reference standard
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: HWI
• storage condition: under inert gas
• application(s): food and beverages
• storage temp.: −20°C
• SMILES string: Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
• InChI: 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
• InChI key: TZBJGXHYKVUXJN-UHFFFAOYSA-N

Description

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference standard in the analysis of herbal medicinal products.

Biochem/physiol Actions

Inhibitor of tyrosine protein kinase; competitive inhibitor of ATP in other protein kinase reactions. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis.

Other Notes

This compound is commonly found in plants of the genus: glycyrrhiza

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable