SCC074
UM-SCC-17A Squamous Carcinoma Cell Line
Human
Synonym(s):
UMSCC17A
HNSCC
Head and neck squamous cell carcinoma cell line
H&N squamous cell carcinoma cell line
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About This Item
UNSPSC Code:
41106514
eCl@ss:
32011203
NACRES:
NA.75
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product name
UM-SCC-17A Squamous Carcinoma Cell Line, UM-SCC-17A is a unique head and neck squamous carcinoma cell line isolated from the primary laryngeal carcinoma of a 48-year old female patient who failed to respond to radiation therapy and is a suitable in vitro model of H&N carcinoma studies.
biological source
human
Quality Level
technique(s)
cell culture | mammalian: suitable
shipped in
dry ice
General description
All UM-SCC cell lines were derived in the lab of Dr. Thomas Carey at the University of Michigan and are exclusively distributed by Merck KGaA, Darmstadt, Germany. Access to UM-SCC cells is limited solely to those officers, employees and students of PURCHASER’s institution who need access to perform research. PURCHASER may not distribute UM-SCC cells or derivatives to third parties. PURCHASER shall comply with all applicable laws in its use and handling of the Product and shall keep it under reasonable safe and secure conditions to prevent unauthorized use or access.
THIS PRODUCT IS ONLY AVAILABLE FOR SALE TO ACADEMIC INSTITUTIONS OR NOT-FOR-PROFIT ENTITIES FOR USE UNDER THIS LIMITED USE LABEL LICENSE. FOR INFORMATION ON COMMERCIAL LICENSING OF UM-SCC CELLS, INCLUDING LICENSING TO COMMERCIAL ENTITIES, PLEASE CONTACT: licensing@emdmillipore.com
THIS PRODUCT IS ONLY AVAILABLE FOR SALE TO ACADEMIC INSTITUTIONS OR NOT-FOR-PROFIT ENTITIES FOR USE UNDER THIS LIMITED USE LABEL LICENSE. FOR INFORMATION ON COMMERCIAL LICENSING OF UM-SCC CELLS, INCLUDING LICENSING TO COMMERCIAL ENTITIES, PLEASE CONTACT: licensing@emdmillipore.com
UM-SCC-17A is a unique head and neck squamous carcinoma cell line isolated from the primary laryngeal carcinoma of a 48-year old female patient who failed to respond to radiation therapy. The tumor persisted and metastasized to the neck, from where the UM-SCC-17B cell line was derived from. The patient achieved long-term remission after surgery . UM-SCC-17A is negative for HPV-16, HPV-18, Hepatitis A, B, C, HIV-1 & 2 viruses and grows as tightly packed colonies or islands.
UM-SCC-17A was established at the University of Michigan with written informed consent obtained from the patient and with the approval of the study by the Medical School Institutional Review Board.
UM-SCC-17A was established at the University of Michigan with written informed consent obtained from the patient and with the approval of the study by the Medical School Institutional Review Board.
Cell Line Description
Endothelial Cells
Application
This product is available for sale to academic institutions or not-for-profit entities for research use. For information on commercial licensing please contact licensing@emdmillipore.com.
Quality
• Each vial contains ≥ 1X106 viable cells.
• Cells are tested by PCR and are negative for HPV-16, HPV-18, Hepatitis A, B, C and HIV-1 & 2 viruses.
• Cells are negative for mycoplasma contamination.
• Each lot of cells are genotyped by STR analysis to verify the unique identity of the cell line.
• Cells are tested by PCR and are negative for HPV-16, HPV-18, Hepatitis A, B, C and HIV-1 & 2 viruses.
• Cells are negative for mycoplasma contamination.
• Each lot of cells are genotyped by STR analysis to verify the unique identity of the cell line.
Storage and Stability
UM-SCC-17A cells should be stored in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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T E Carey et al.
Cancer research, 49(21), 6098-6107 (1989-11-01)
The squamous cell carcinoma (SCC) cell lines UM-SCC-17A and -17B were derived, respectively, from the primary laryngeal cancer and a metastatic neck tumor of a patient who failed to respond to radiation therapy but achieved long-term remission after surgery. The
J Chad Brenner et al.
Head & neck, 32(4), 417-426 (2009-09-18)
We established multiple University of Michigan Squamous Cell Carcinoma (UM-SCC) cell lines. With time, these have been distributed to other labs all over the world. Recent scientific discussions have noted the need to confirm the origin and identity of cell
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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