MAB10139
Anti-LIM Domain Only 2 Antibody, clone 2E6
culture supernatant, clone 2E6, Chemicon®
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
2E6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... LMO2(4005)
General description
LIM Domain only 2 (LMO2) encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur.
Specificity
Human
Immunogen
Recombinant human LMO2
Application
Detect LIM Domain Only 2 using this Anti-LIM Domain Only 2 Antibody, clone 2E6 validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Developmental Signaling
Developmental Signaling
Quality
Routinely evaluated by immunoblot.
Target description
18kDa
Physical form
Liquid containing 0.1% sodium azide.
Storage and Stability
1 year at 4°C from date of shipment
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
nwg
Certificates of Analysis (COA)
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Yasodha Natkunam et al.
Blood, 109(4), 1636-1642 (2006-10-14)
We previously developed a multivariate model based on the RNA expression of 6 genes (LMO2, BCL6, FN1, CCND2, SCYA3, and BCL2) that predicts survival in diffuse large B-cell lymphoma (DLBCL) patients. Since LMO2 emerged as the strongest predictor of superior
The significance of LMO2 expression in the progression of prostate cancer
Ma, S, et al
The Journal of Pathology, 211, 278-285 (2007)
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