GF302
BMP-4 Protein, Human Recombinant Animal Free
Bone morphogenetic protein 4 (BMP4) is a TGFβ superfamily lig& that is widely expressed from early embryogenesis through adulthood. The Recombinant animal free human BMP-4 protein is manufactured using all non-animal reagents.
Synonym(s):
BMP4, Bone morphogentic protein-4, DVR-4
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77
Recommended Products
recombinant
expressed in E. coli
Quality Level
assay
>98% (SDS-PAGE and HPLC)
impurities
<0.1 μg/mg protein endotoxin (<1EU/μg)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
Bone morphogentic protein 4 (BMP4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
Animal free human recombinant BMP4 is a fully active homodimeric protein consisting of two 107 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Animal free human recombinant BMP4 is a fully active homodimeric protein consisting of two 107 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Product Source: E. coli
Specificity
Cross Reactivty
Mouse
Mouse
Application
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Quality
Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Physical form
Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human BMP-4 is manufactured using all non-animal reagents
Storage and Stability
Store at -20°C for up to 6 months from date of receipt.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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