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CBL242

Sigma-Aldrich

Anti-Glucose Transporter GLUT-1 Antibody, CT

Chemicon®, from rabbit

Synonym(s):

Anti-Anti-CSE, Anti-Anti-DYT17, Anti-Anti-DYT18, Anti-Anti-DYT9, Anti-Anti-EIG12, Anti-Anti-GLUT, Anti-Anti-GLUT-1, Anti-Anti-GLUT1, Anti-Anti-GLUT1DS, Anti-Anti-HTLVR, Anti-Anti-PED, Anti-Anti-SDCHCN

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_006516.1

UniProt accession no.

P11166

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SLC2A1(6513)

Specificity

Specific for human glucose transporter 1 from muscle and adipose tissue. Does not cross-react with GLUT-4. The molecular weight of the glucose transporter precipitated by the serum is approximately 46 kDa.

Immunogen

12 amino acid peptide of the C-terminus of hGLUT-1 {LFHPLGADSQV} conjugated to KLH
Epitope: C-terminus

Application

Anti-Glucose Transporter GLUT-1 Antibody, C-terminus detects level of Glucose Transporter GLUT-1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling
Western blot analysis of GLUT-1 activity in adipose and muscle tissue (5μg/ml)

Immunoprecipitation of GLUT-1 (5μg/ml)

Optimal working dilutions must be determined by the end user.

Target description

46 kDa

Physical form

ImmunoAffinity Purified
The polyclonal is presented in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Storage and Stability

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year.

Analysis Note

Control
Colorectal carcinoma

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M G Alves et al.
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The Journal of experimental medicine, 218(4) (2021-02-04)
The low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic and cell signaling transmembrane protein. Endothelial LRP1 clears proteinaceous toxins at the blood-brain barrier (BBB), regulates angiogenesis, and is increasingly reduced in Alzheimer's disease associated with BBB breakdown and neurodegeneration.
Sugar transporter regulation by ATP and quaternary structure.
Cloherty, E K, et al.
Blood Cells, Molecules and Diseases, 27, 102-107 (2001)
In vitro simulation of calorie restriction-induced decline in glucose and insulin leads to increased insulin-stimulated glucose transport in rat skeletal muscle.
Arias, EB; Cartee, GD
American Journal of Physiology. Endocrinology and Metabolism null
Gonçalo R Silva et al.
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The present work evaluated the anticancer properties of sweet cherry (Prunus avium) extract on human prostate cells. Several sweet cherry cultivars from Fundão (Portugal) were methanol-extracted and their phytochemical composition characterized. The Saco "late harvest" extract was highly-enriched in anthocyanins
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