ABN472

Anti-TFEB Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35, TFEB
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): western blot: suitable
• UniProt accession no.: P19484
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... TFEB(7942)

Description

General description

Transcription factor EB (TFEB) is a member of the MiT/TFE family of transcription factors that is translocated in a subset of renal tumors. It plays an important role in the signal transduction process required for normal vascularization of the placenta. TFEB specifically recognizes and binds the E-box sequence (5′-CANNTG-3′) and CLEAR box sequence (5′-GTCACGTGAC-3′).

Immunogen

KLH-conjugated linear peptide corresponding to human TFEB.

Application

Detect TFEB using this rabbit polyclonal antibody, Anti-TFEB Antibody validated for use in western blotting.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Quality

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TFEB in 15 µg of A549 cell lysate.

Target description

~57 kDa observed. Uniprot describes two isoforms at ~44 kDa and ~53 kDa Uncharacterized bands may appear in some lysates.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
A549 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable