ABN262

Anti-Trypsin-3 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI accession no.: NP_031369
• UniProt accession no.: P35030
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... PRSS3(5646)

Description

General description

Trypsin-3 is also called Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, and Trypsin IV and belongs to the peptidase S1 family. Trypsin-3 is a digestive protease that specifically degrades trypsin inhibitors and may be involved in the processing of defensins, including DEFA5, in the ileum. Trypsin-3 is expressed in pancreas, brain and in Paneth cells, at the base of small intestinal crypts.

Specificity

Other homologies: Rat (82% sequence homology), Mouse (72% sequence homology).

Immunogen

KLH-conjugated linear peptide corresponding to the human Trypsin-3.

Application

Anti-Trypsin-3 Antibody is a highly specific rabbit polyclonal antibody, that targets Trypsin & has been tested in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Trypsin-3 in human pancreatic, cerebellum, and thalamus tissues.

Quality

Evaluated by Western Blotting in human pancreas tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Trypsin-3 in 10 µg of human pancreas tissue lysate.

Target description

~26 kDa observed. Four isoforms are known to exist due to alternative splicing.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable