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Key Documents

AB9726

Sigma-Aldrich

Anti-Serotonin Transporter Antibody

serum, Chemicon®

Synonym(s):

Serotonin transporter antibody

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_001045.3

UniProt accession no.

P31645

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... HTT(3064) , SLC6A4(6532)

Specificity

Serotonin Transporter. By Western blot the antibody recognizes a strong band at ~64 kDa in rat brain extract. The antibody is suitable for detection of the serotonin transporter in the CNS, PNS and peripheral organs where the transporter is present.

Immunogen

Fusion protein from the N-terminal of rat Serotonin Transporter.

Application

Anti-Serotonin Transporter Antibody is an antibody against Serotonin Transporter for use in IH, IP & WB.
Immunohistochemistry on 4% paraformaldehyde fixed tissues.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Physical form

Liquid

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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F C Zhou et al.
Brain research. Developmental brain research, 119(1), 33-45 (2000-01-29)
Serotonin transporter (5-HTT), a transmembrane protein, has been shown in adult brain to be distributed not only on synaptic terminals but to a great extent on axons as well. Here we report the ontogeny of 5-HTT and its relationship with
Interleukin-15 affects serotonin system and exerts antidepressive effects through IL15R? receptor.
Wu, X; Hsuchou, H; Kastin, AJ; He, Y; Khan, RS; Stone, KP; Cash, MS; Pan, W
Psychoneuroendocrinology null
F C Zhou et al.
Brain research, 805(1-2), 241-254 (1998-09-12)
The serotonin (5-HT) transporter (5-HTT) is known to play a role in depression and many 5-HT related diseases, and is the target site for drugs of abuse, such as cocaine, MDMA, and methamphetamine. The major role of the 5-HTT has
Serotonergic receptor upregulation in cerebral cortex and down regulation in brainstem of streptozotocin induced diabetic rats: antagonism by pyridoxine and insulin.
Pretty Mary Abraham,T R Anju,S Jayanarayanan,C S Paulose
Neuroscience Letters null
Serotonin transporter antibodies: production, characterization, and localization in the brain.
Zhou, F C, et al.
Brain Research Molecular Brain Research, 43, 267-278 (1996)
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