AB1975
Anti-Enkephalin, Met Antibody
serum, Chemicon®
Synonym(s):
Anti-PE, Anti-PENK-A
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
suitability
not suitable for Western blot
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
rat ... Penk(29237)
General description
Met Enkephalin is an endogenous opioid peptide neurotransmitter found naturally in the brains of many animals, including humans. Methionine enkephalin (Met Enkephalin) is a pentapeptide that appears to enhance immune function at low doses and suppress at high doses. This molecule acts in the central nervous, neuroendocrine, and immune systems. During development of the brain Met Enkephalin is thought to act as a growth factor. Met Enkephalin may be capable of enhancing immune function in cancer or AIDS patients.
Specificity
Met-enkephalin
Immunogen
Met-enkephalin, Hemocyanin conjugate.
Application
Immunohistochemistry (with immunoperoxidase detection *): 48 hour incubation, 4°C.
Spinal cord nerve fibers (rat): 1:2,000-1:4,000.
Immunofluorescence*: overnight incubation, +2-8°C
Duodenum endocrine cells & nerve fibers (pig): 1:2,000
Ileum endocrine cells & nerve fibers μguinea pig): 1:4,000.
*fixative-any cross-linking reagent
Optimal working dilutions must be determined by the end user.
Spinal cord nerve fibers (rat): 1:2,000-1:4,000.
Immunofluorescence*: overnight incubation, +2-8°C
Duodenum endocrine cells & nerve fibers (pig): 1:2,000
Ileum endocrine cells & nerve fibers μguinea pig): 1:4,000.
*fixative-any cross-linking reagent
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuroinflammation & Pain
Hormones & Receptors
Neuroinflammation & Pain
Hormones & Receptors
This Anti-Enkephalin, Met Antibody is validated for use in IH for the detection of Enkephalin.
Target description
0.6 kDa
Linkage
Replaces: AB5026
Physical form
Serum in 0.05% Sodium Azide
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
Tested on rat brain/coronal section
Tested on rat brain/coronal section
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
Certificates of Analysis (COA)
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Heinz Künzle
Journal of anatomy, 212(6), 795-816 (2008-05-31)
Although there are remarkable differences regarding the output organization of basal ganglia between mammals and non-mammals, mammalian species with poorly differentiated brain have scarcely been investigated in this respect. The aim of the present study was to identify the pallidal
K J Dougherty et al.
Neuroscience, 163(3), 909-919 (2009-06-30)
The synthesis enzyme glutamic acid decarboxylase (GAD65 or GAD67) identifies neurons as GABAergic. Recent studies have characterized the physiological properties of spinal cord GABAergic interneurons using lines of GAD67-green fluorescent protein (GFP) transgenic mice. A more complete characterization of their
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