AB10541

Anti-Galectin-3 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rhesus macaque, human
• species reactivity (predicted by homology): rhesus monkey (based on 100% sequence homology)
• technique(s): western blot: suitable
• NCBI accession no.: NP_002297
• UniProt accession no.: P17931
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... LGALS3(3958)

Description

General description

Galectin-3 belongs to the galectin gene family, which is defined by the specificity of a carbohydrate recognition domain (CRD) for Gal/Lac. Galectin-3 expression is usually elevated in a wide range of neoplastic cell types. The galectin CRD consists of 135 amino acids. Galectin-3 is known to play a role in tumor development, apoptosis, and cell cycle progression.

Specificity

This antibody recognizes the Pro64 mutation domain of Galectin-3. It is equally specific for wild-type or mutant His64 Galectin-3.

Immunogen

Epitope: Pro64 mutation domain

KLH-conjugated linear peptide corresponding to the Pro64 mutation domain of human Galectin-3.

Application

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-Galectin-3 Antibody is validated for use in WB for the detection of Galectin-3.

Quality

Evaluated by Western Blot in MG-63 cell lysate.

Western Blot Analysis: A 1:250 dilution of this antibody detected Galectin-3 in 10 µg of MG-63 cell lysate.

Target description

~33 kDa observed

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
MG-63 cell lysate

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable