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Key Documents

8.55020

Sigma-Aldrich

Aminomethylated polystyrene HL (100-200 mesh)

Novabiochem®

Synonym(s):

AM resin HL (100-200 mesh)

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About This Item

UNSPSC Code:
13111023
NACRES:
NA.22

Quality Level

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

General description

Base amino-functionalized polystyrene resin. Can be loaded with linkers bearing carboxylic acid functionalities.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 01-64-0143

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Swelling Volume (in DMF): lot specific reslut
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.50 - 1.50 mmol/g
TNBS-Test (positive): passes test
TNBS-Test (after loading with Fmoc-Leu-OH (negative)): passes test
The polymer matrix is copoly (styrene -1% DVB), 100 -200 mesh.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

The most popular reagent for cleavage of peptides from Boc-based resins is anhydrous HF. Of all the cleavage procedures HF appears to be the most versatile and least harmful to a wide variety of peptides synthesized on Boc-based resins.

Related Content

The Novabiochem® product line has one of the most extensive ranges of polymer-supports for solid phase peptide synthesis. They range from high-loaded, lows welling for the large-scale production of relatively short peptides to high-swelling, low-loaded for the synthesis of long or difficult sequences.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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