8.51206

TSTU

≥97.0% (NMR), for peptide synthesis, Novabiochem^®

• Synonym(s): TSTU, N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate, O-[N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate
• Empirical Formula (Hill Notation): C₉H₁₆BF₄N₃O₃
• CAS Number: 105832-38-0
• Molecular Weight: 301.05
• MDL number: MFCD00077875
• UNSPSC Code: 12352107
• NACRES: NA.22

Properties

• product name: TSTU, Novabiochem^®
• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥97.0% (NMR)
• form: powder or crystals
• reaction suitability: reaction type: Coupling Reactions
• manufacturer/tradename: Novabiochem^®
• mp: 195-200 °C
• application(s): peptide synthesis
• storage temp.: 2-8°C
• InChI: 1S/C9H16N3O3.BF4/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;2-1(3,4)5/h5-6H2,1-4H3;/q+1;-1
• InChI key: YEBLHMRPZHNTEK-UHFFFAOYSA-N

Description

General description

Useful reagent for the conversion of carboxylic acids to water soluble OSu esters ^{[1, 2]}. Ideal for the conversion of dyes and PEG building blocks to the corresponding active esters for coupling in aqueous media.

Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents

Literature references

^[1] W. Bannwarth, et al. (1988) Helv. Chim. Acta, 71, 2085.
^[2] R. Knorr, et al. (1989) Tetrahedron Lett., 30, 1927.

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder to crystals
Purity (NMR): ≥ 97.0 %
Identity (IR): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1A
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable