8.51031

Fmoc-NH-(PEG)₂-COOH (20 atoms)

≥92.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonym(s): Fmoc-NH-(PEG)₂-COOH (20 atoms), O-(N-Fmoc-3-aminopropyl)-O′-(N-diglycolyl-3-aminopropyl)-diethyleneglycol
• Empirical Formula (Hill Notation): C₂₉H₃₈N₂O₉
• CAS Number: 916585-44-9
• Molecular Weight: 558.62
• UNSPSC Code: 12352106
• NACRES: NA.22

Properties

• product name: Fmoc-NH-(PEG)₂-COOH (20 atoms), Novabiochem^®
• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥92% (TLC); ≥92.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Pegylations
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C

Description

General description

Fmoc-NH-(PEG)₂-COOH is a bifunctional 20 atom PEG spacer. It can be introduced using standard coupling methods, such as PyBOP^®, HBTU or TBTU, and is compatible with standard TFA cleavage protocols.

Literature references

^[1] B. Baumeister, et al. (2003) Biopolymers, 71, 339.
^[2] V. Kumar & J. Aldrich (2003) Org. Lett., 5, 613.
^[3] E. Agner, et al. in ′Peptides 2000, Proc. 26th European Peptide Symposium′, Paris, J. Martinez & J.-A- Fehrentz, 2001, pp. 1011.

Application

Fmoc-NH-(PEG)₂-COOH (20 atoms) Novabiochem^®. CAS 916585-44-9, molar mass 558.62 g/mol.

Linkage

Replaces: 01-63-0141

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(0110)): ≥ 92 %
Assay (HPLC, area%): ≥ 92.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable