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Key Documents

605206

Sigma-Aldrich

Thrombin, Citrate-Free, Human Plasma

Synonym(s):

Thrombin, Citrate-Free, Human Plasma

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

human plasma

Quality Level

form

liquid

specific activity

≥2500 NIH units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Native thrombin from human plasma. Formulation useful for procedures in which the presence of citrate is undesirable.
Native thrombin from human plasma. Key enzyme in the coagulation cascade. Converts fibrinogen to fibrin and activates factor XIII, which cross-links and stabilizes the fibrin polymer. Formulation useful for procedures in which presence of citrate is undesirable.

Warning

Toxicity: Harmful (C)

Unit Definition

One unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.

Physical form

In 100 mM NaCl, 20 mM Tris-HCl, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

Homogeneous by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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