5.00469

S107

≥98% (HPLC), solid, RyR-Calstabin interaction stabilizer, Calbiochem^®

• Synonym(s): RyR-Calstabin Interaction Stabilizer, S107, 7-methoxy-4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine, Ryanodine Receptor Stabilizer, Rycal S107
• Empirical Formula (Hill Notation): C₁₁H₁₅NOS
• CAS Number: 927871-76-9
• Molecular Weight: 209.31
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• product name: RyR-Calstabin Interaction Stabilizer, S107,
• assay: ≥98% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: off-white
• solubility: DMSO: 100 mg/mL
• storage temp.: 2-8°C

Description

General description

RyR-Calstabin Interaction Stabilizer, S107 can protect hippocampal neurons from GABAergic synaptic changes caused by Abeta42 oligomers.

Application

RyR-Calstabin Interaction Stabilizer, S107 has been used in culture media for hypoxic exposures to study the impact of hypoxia on sarcoplasmic reticulum calcium leakage and expression of ryanodine receptor2 (RyR2).

Biochem/physiol Actions

Primary Target
RyR2

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable