494126

Ghrelin, Human, Synthetic

The 28-amino acid n-octanoylated (at ser3) natural peptidyl ligand for the growth hormone secretagogue receptor 1a (GHSR1a).

• Synonym(s): Ghrelin, Human, Synthetic, H₂N-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR-CO₂H
• Empirical Formula (Hill Notation): C₁₄₉H₂₄₉N₄₇O₄₂
• CAS Number: 304853-26-7
• Molecular Weight: 3370.86
• UNSPSC Code: 12352200
• NACRES: NA.51

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C

Description

General description

The 28-amino acid n-octanoylated (at ser3) natural peptidyl ligand for the growth hormone secretagogue receptor 1a (GHSR1a). Ghrelin is secreted predominantly in the stomach and stimulates growth hormone release from the pituitary gland.

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

H-Gly-Ser-Ser(n-Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Kojima, M. 2008. Regul. Pept.145, 2.
Wu, J.T., and Kral, J.G. 2004. Ann. Surg.239, 464
Kojima, M., et al. 1999. Nature402, 656.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable