444215

MMP-2/MMP-9 Substrate I, Fluorogenic

A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9).

• Synonym(s): MMP-2/MMP-9 Substrate I, Fluorogenic, Gelatinase A/Gelatinase B Substrate I, DNP-PLGMWSR
• Empirical Formula (Hill Notation): C₄₄H₆₁N₁₃O₁₃S
• Molecular Weight: 1012.10
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: yellow
• solubility: DMSO: soluble
• fluorescence: λ_ex ~280 nm; λ_em ~360 nm
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9) (excitation maximum: 280 nm; emission maximum: 360 nm).

A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9).

Biochem/physiol Actions

Cell permeable: no

Primary Target
A fluorogenic substrate for both human fibroblast gelatinase (HFG; MMP-2) and human neutrophil gelatinase (HNG; MMP-9).

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Sequence

DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.

Other Notes

Netzel-Arnett, S., et al. 1991. Anal. Biochem. 195, 86.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable