420318

Kainic Acid

≥98% (HPLC), solid, amino acid receptor agonist, Calbiochem^®

• Synonym(s): Kainic Acid, 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
• Empirical Formula (Hill Notation): C₁₀H₁₅NO₄
• CAS Number: 487-79-6
• Molecular Weight: 213.23
• UNSPSC Code: 12352106
• NACRES: NA.77

Properties

• product name: Kainic Acid, An excitatory amino acid receptor agonist selective for the kainate receptor subtype (K_i = 21 nM for ³H-kainate binding in rat striatum).
• Quality Level: 200
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: off-white
• solubility: dilute base: 10 mg/mL; water: 10 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
• InChI key: VLSMHEGGTFMBBZ-OOZYFLPDSA-N

Description

General description

An excitatory amino acid receptor agonist selective for the kainate receptor subtype (K_i = 21 nM for ³H-kainate binding in rat striatum). Also activates AMPA receptors.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Kainate receptor subtype

Product does not compete with ATP.

Reversible: no

Target K_i: 21 nM for 3H-kainate binding in rat striatum

Warning

Toxicity: Harmful (C)

Other Notes

Niu, L., et al. 1996. Biochemistry35, 2030.
Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable