MilliporeSigma
All Photos(3)

1.37039

SAFC

Potassium dihydrogen phosphate

crystalline, Ph. Eur., BP, JPC, NF

Synonym(s):
prim.-Potassium phosphate, mono-Potassium orthophosphate, Potassium biphosphate, Potassium phosphate monobasic, Potassium phosphate monobasic, Monopotassium phosphate, Potassium dihydrogen phosphate
Linear Formula:
KH2PO4
CAS Number:
Molecular Weight:
136.09
MDL number:
EC Index Number:
231-913-4

Quality Level

Agency

BP
JPC
NF
Ph. Eur.

product line

EMPROVE® EXPERT

assay

≥99.0% dry basis (alkalimetric)
98.0-100.5% (alkalimetric)

form

crystalline
solid

pH

4.2-4.6 (20 °C, 20 g/L in H2O)

mp

252.6 °C (lit.)

density

2.338 g/mL at 25 °C (lit.)

application(s)

biopharma process and formulation
liquid formulation
parenterals
pharmaceutical

storage temp.

2-30°C

SMILES string

[K+].OP(O)([O-])=O

InChI

1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

GNSKLFRGEWLPPA-UHFFFAOYSA-M

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Potassium dihydrogen phosphate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Potassium dihydrogen phosphate Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Material Qualification Dossier

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Quality Management Dossier

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Operational Excellence Dossier

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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