1.11037

tri-Sodium citrate

anhydrous, EMPROVE^® ESSENTIAL, USP, FCC, E 331

• Synonym(s): tri-Sodium citrate
• Empirical Formula (Hill Notation): C₆H₅Na₃O₇
• CAS Number: 68-04-2
• Molecular Weight: 258.07
• MDL number: MFCD00012462
• UNSPSC Code: 12352107
• E Number: E331
• EC Index Number: 200-675-3

Properties

• agency: USP
• Quality Level: 500
• reg. compliance: FCC
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 7.5-9.0 (20 °C, 10 g/L in H₂O)
• mp: 150 °C (decomposition)
• solubility: 425 g/L
• density: 1.76 g/cm³ at 18 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• InChI: 1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3
• InChI key: HRXKRNGNAMMEHJ-UHFFFAOYSA-K

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1